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STD Testing by Condition – What to Test For and When

STD Testing by Condition

Not sure which STD test is right for your situation? This page organizes testing options by condition, so you can focus on what matters most — the type of infection you’re concerned about. Whether you’ve had a recent exposure, developed symptoms, or just want a routine screen, knowing how each condition is tested can help you make faster, more informed decisions.

Different STDs require different sample types — from blood and urine to genital swabs — and some may only show up on certain tests depending on timing or symptoms. Some providers bundle multiple tests together in panels, while others let you choose individual tests based on your specific risk or concern.

Below, you’ll find brief explanations for each major STD — what the test looks for, when to take it, and how results are typically delivered. You can also explore condition-specific pages with more detail and provider recommendations.

Herpes Testing

Herpes testing is used to detect HSV-1 and HSV-2, the viruses that cause oral and genital herpes. If you’re showing symptoms like sores or blisters, a swab test from an active lesion is usually the best option. If you’ve never had symptoms but want to know your status, a blood test can check for past exposure. Herpes tests are widely available and may be included in some lab panels, though not all providers offer it by default.

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HIV Testing

HIV tests check for antibodies, antigens, or viral RNA in the bloodstream. Some tests can detect HIV just 10–14 days after exposure, while others work best after 3–4 weeks. Early detection tests are usually lab-based, but standard HIV screening is also available through at-home kits. This is one of the most important routine STD tests, and many providers include it in their core screening packages.

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Chlamydia & Gonorrhea Testing

Chlamydia and gonorrhea are often tested together using a single urine or swab sample. These infections are highly contagious, frequently asymptomatic, and easy to treat once diagnosed. Most test panels include both automatically, whether you’re using a lab or ordering an at-home kit. If you’ve recently had unprotected sex or a new partner, this is one of the best tests to take first.

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Syphilis Testing

Syphilis is tested using a blood sample that checks for antibodies produced in response to the infection. It’s often included in 4-panel or 10-panel STD tests. Because syphilis can progress in stages, testing may be repeated over time to confirm active infection or past exposure. Early treatment is highly effective, so don’t delay testing if you’ve had symptoms or known exposure.

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Trichomoniasis Testing

Trichomoniasis, or “trich,” is a very common but often overlooked STD. It’s caused by a parasite and is typically tested with a urine or vaginal swab sample. While symptoms like itching, discharge, or discomfort may be present, many cases go undetected without routine testing. Trich is included in some at-home panels and can also be ordered individually through select labs.

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Hepatitis B & C Testing

Hepatitis B and C are bloodborne viruses that affect liver function. While not always sexually transmitted, they can be passed through bodily fluids and are recommended for testing in at-risk groups. A simple blood test can determine if you’ve been exposed or are actively infected. Some providers include hepatitis screening in full STD panels; others offer it as a standalone test.

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Mycoplasma Genitalium Testing

Mycoplasma Genitalium is an emerging STD that can be difficult to detect and treat if left untested. It’s not included in most standard STD panels, so you’ll need to look for a provider that offers it as a specific add-on. Testing usually requires a urine or swab sample and is recommended if you have persistent symptoms after ruling out more common infections.

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HPV Testing

HPV (human papillomavirus) is the most common STI in the U.S. High-risk strains can lead to cervical cancer, which is why testing is typically recommended for women 30 and older. Some at-home kits offer HPV screening, though lab-based Pap and co-tests are still the most comprehensive options. There’s no standard HPV test for men yet, but researchers continue to explore options.

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